Cardiovascular
Lauren Tezak
Texas Childrens Hospital
Disclosure(s): No relevant financial relationship(s) to disclose.
Atrial fibrillation (AF) has a prevalence of 5% to 15% in general ICU populations and up to 46% in patients with septic shock. AF is associated with stroke, heart failure, prolonged hospital stay, and increased mortality. Recent guidelines suggest replacing the ABC approach (avoid stroke, better symptom control, cardiovascular and comorbidity management) with the CARE approach (address comorbidities, avoid stroke and thromboembolism, rate and rhythm control, evaluation and reassessment). This approach focuses first on comorbidities and predisposing conditions. This session will focus on each component. Cardiovascular and other comorbidities may need to be addressed first to optimize symptom and rate control and facilitate maintenance of sinus rhythm, either with spontaneous reversion or after potential cardioversion. Risk assessment for stroke has been simplified by use of the CHA2DS2-VA, which now uses the same cutoff for men and women. The decision between rate and rhythm control is complex and depends on hemodynamics, cardiac functional and structural abnormalities, the reason for ICU admission, and ongoing ICU problems. Evaluation of patient trajectories is key to individualization of therapy.
Brittany Turpin, PharmD, PhD, BCCCP (she/her/hers) – Wolters Kluwer Health
Bryan Marchant, MD – Wake Forest Baptist Medical Center
Sabrina Dunham, PharmD, BCPS, BCCP – University of Michigan Health System