Epidemiology Outcomes
Laura Evans, MD, MSc, FCCM
University of Washington Medical Center, Washington
Disclosure information not submitted.
Acute respiratory distress syndrome (ARDS) is an acute inflammatory syndrome of the lungs leading to fluid leakage and respiratory failure. Etiologies of ARDS include trauma, inhalation injuries, respiratory infections, and sepsis. In the United States, approximately 10% of ICU patients are thought to have ARDS, with an approximate 40% mortality rate. There are no FDA-approved therapies for ARDS. Clinical management relies on treating the underlying cause and supportive care (e.g., lung ventilation, extracorporeal membrane oxygenation, corticosteroids, fluid management, inflammation reduction). Many drugs have been studied with little success. Clinical failure is thought to be due to ARDS' heterogeneity. Recent research has demonstrated the ability to subtype or endotype patients with ARDS, which could be used to support clinical trials and guide therapies. Speakers will explore some of the research on ARDS subtyping and potential impacts on changing patient prognoses.
Christopher Lindsell, Ph.D (he/him/his)
Michael Matthay (he/him/his)
Diego A. Rey, PhD – Endpoint Health Inc
Kimberly Sciarretta (she/her/hers)