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Pharmacology
Concurrent

Derm-emergencies: Updates to Skin and Soft Tissue Emergencies

Tuesday, March 24, 2026
9:45 AM - 10:45 AM Central Time
Location: W187

    Concurrent Session Moderator(s)

  • AG

    Anthony Gerlach, PharmD, FCCM

    Ohio State University Wexner Medical Center, Ohio

    Disclosure(s): No relevant financial relationship(s) to disclose.

Skin and soft tissue emergencies vary by type, severity, and frequency, and cause, including infection or drug reactions. Some can be fatal, so it is essential for clinicians to be up to date on diagnosis and treatment options. Because severe drug reactions, such as Stevens-Johnson Syndrome and toxic epidermal necrolysis, are rare, published literature is scarce on treatment options. Some literature is emerging on the use of biologic agents in addition to traditional treatments for these drug reactions. Frostbite is a seasonal and regional emergency that can result from cold exposure and cause loss of tissue and function with need for amputation in severe cases. Acute management is key in helping to preserve tissue. Necrotizing fasciitis, along with the risk of toxic shock, can be fatal or necessitate debridement and amputation. Because of the risk of toxic shock, antibiotics may be used for toxin binding purposes. New data have been published on the possible role of linezolid in place of the traditional antibiotic, clindamycin, for toxic shock syndrome.

Learning Objectives:

  • Evaluate the role of biologic agents in the management of dermatologic emergencies
  • Describe acute phase treatment options and strategies for management of frostbite
  • Compare adjunct antibiotic treatment options for toxin binding in necrotizing fasciitis with toxic shock syndrome

Presentations:

  • 9:50 AM - 10:05 AM Central Time
    Emerging Therapy for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

    Ann B. Prazak, PharmD, BCPS, BCCCP – University of Utah

  • 10:05 AM - 10:20 AM Central Time
    Frozen Solid: Frostbite Management

    Ryan Fey, MD – Hennepin County Medical Center

  • 10:20 AM - 10:35 AM Central Time
    Linezolid Versus Clindamycin for Necrotizing Fasciitis

    Sameer Kadri, MD, MS – National Institutes of Health Clinical Center