2026 Critical Care Congress Skip to main content
2026 Critical Care Congress Main banner
Final Program


Advance Program
Icon Legend
This session is not in your schedule.
This session is in your schedule. Click again to remove it.
Session Icons
Thought Leader Session
Thought Leader Session
Guidelines Session
Guidelines Session
Aging Adult Track
Aging Adult Track
Additional Registration Fee
Additional Registration Fee

Research Snapshot Theater: Cardiovascular, Adult VIII

LUCAS vs Manual CPR in Obese In-Hospital Cardiac Arrest: Survival Outcome

Monday, March 23, 2026
2:30 PM - 3:30 PM Central Time
Location: Connections Central - RST 02

  • Aryan Pathak, BS (he/him/his)

    Florida

    Disclosure(s): No relevant financial relationship(s) to disclose.

  • Ivan Huespe, MD

    Buenos Aires, Argentina

    Disclosure(s): No relevant financial relationship(s) to disclose.

  • AP

    Aayushi Pareek, MD

    Research Trainee
    Mayo Clinic, Jacksonville, Florida

    Disclosure information not submitted.

  • JS

    Jorge Sinner, MD

    Physician
    Hospital Italiano de Buenos Aires, Argentina

    Disclosure information not submitted.

  • Saurabh Sujanyal, MBBS

    Disclosure(s): No relevant financial relationship(s) to disclose.

  • SB

    Said Bateh, B.S

    Research Trainee
    Mayo Clinic, Jacksonville, Florida

    Disclosure information not submitted.

  • JD

    Jose Delgado, MD

    Research Fellow
    Mayo Clinic, Jacksonville, Florida

    Disclosure information not submitted.

  • Anek Jena, n/a

    Illinois

    Disclosure(s): No relevant financial relationship(s) to disclose.

  • Rosa Corro, MD (she/her/hers)

    Mayo Clinic Hospital in Florida, Florida

    Disclosure(s): No relevant financial relationship(s) to disclose.

  • FS

    Faiz Saleem, MD

    Research Fellow
    Mayo Clinic, Jacksonville, Florida

    Disclosure information not submitted.

  • Vrutti Patel, BS (she/her/hers)

    Florida

    Disclosure(s): No relevant financial relationship(s) to disclose.

  • DT

    Deeksha Thatigolla, MBBS

    Research Trainee
    Mayo Clinic, Jacksonville, Florida

    Disclosure information not submitted.

  • RV

    Raksha Venkatesan, MD

    Fellow
    Mayo Clinic, Jacksonville, Florida

    Disclosure information not submitted.

  • TO

    Titilope Olanipekun, MD, MPH

    Brigham and Women's Hospital, Massachusetts

    Disclosure(s): No relevant financial relationship(s) to disclose.

  • AH

    Abby Hanson, SRNA

    Registered Nurse
    Hospital Italiano de Buenos Aires, Argentina

    Disclosure information not submitted.

  • KS

    Karen Stoner, RN

    Registered Nurse
    Mayo Clinic, Jacksonville, Florida

    Disclosure information not submitted.

  • AS

    Anna Shapiro, MD

    Consultant, Anesthesiology and Critical Care
    Mayo Clinic Florida

    Disclosure information not submitted.

  • Devang Sanghavi, MD, MHA

    Mayo Clinic Hospital in Florida, Florida

    Disclosure information not submitted.

  • PM

    Pablo Moreno Franco, MD

    Chair, Critical Care Medicine
    Mayo Foundation for Medical Education

    Disclosure information not submitted.

  • NK

    Nick Kelly, MD

    Assistant Professor
    Mayo Clinic, Jacksonville, Florida

    Disclosure information not submitted.

Introduction: Obesity is a growing global health concern that not only increases the risk of mortality but also complicates the clinical management of critically ill patients, particularly during cardiopulmonary resuscitation (CPR). This study aims to compare 24-hour and 60-day survival after in-hospital cardiac arrest (IHCA) in overweight (BMI ≥ 25 kg/m²) and obese patients (BMI ≥ 30 kg/m²) resuscitated with LUCAS assisted versus manual CPR, and to determine whether BMI (body mass index) modifies this association.


Methods: Multicenter retrospective cohort of adult IHCA events at seven Mayo Clinic hospitals from January 2019 to January 2025. Cardiac arrests < 4 minutes or without a BMI record were excluded. IPTW (Inverse-probability-of-treatment weighting) adjusted for demographics, arrest location, and comorbidities. We first compared 24-hour and 60-day mortality between groups using IPTW-weighted logistic regression. To assess effect modification by BMI, we fitted analogous models with restricted cubic splines (knots at 25, 28, 37 kg/m²) and LUCAS × BMI interaction terms. The model choice was based on Akaike Information Criterion.


Results: A total of 679 patients were included (manual CPR=595 and LUCAS assisted=84). In weighted analyses, 24-hour mortality did not differ significantly (OR 1.54; 95% CI: 0.94-2.53, p = 0.09), nor did 60-day mortality (OR 1.83; 95% CI: 0.92-3.64, p = 0.09). Spline models showed that 24-hour and 60 days mortality increased modestly between BMI 25-28 kg/m² and then plateaued above 28 kg/m² in both groups. No LUCAS × BMI interaction was significant (all p > 0.14), indicating consistent effects across the BMI spectrum.


Conclusions: In overweight and obese IHCA patients, LUCAS-assisted mechanical CPR did not improve 24-hour or 60-day mortality versus high quality manual compressions, and effectiveness was independent of BMI.