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Final Program


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Thought Leader Session
Thought Leader Session
Guidelines Session
Guidelines Session
Aging Adult Track
Aging Adult Track
Additional Registration Fee
Additional Registration Fee

Jeremy Prokop, PhD (he/him/his)

Michigan

Our team is building a future where precision medicine can utilize complex omic datasets to identify each individual's current state of health and develop patient-specific treatment plans. Every patient matters and omics power us to care for individuals. I support translational research at Corewell Health, Helen DeVos Children's Hospital, and Michigan State University. My lab implements cutting-edge multiomic sequencing platforms (modification-sensitive long-read sequencing, single-cell, spatial, and cytoprofiling), organoid modeling with induced pluripotent stem cells for human tissues, and optimizes workflows for bioinformatics in Linux ecosystems. We assist in many clinical areas, including rare pediatric diseases, adult cardiovascular biology, pregnancy complications, oncology, microbiology, virology, and autism spectrum disorder. In the area of rare diseases, we have led the discovery of the recent LRP1-related disorder, contributed to the drug treatments of ODC1-related disorder, contributed to the advancement of over a dozen unique genetic disorders, assisted in building new payer coverage strategies, and are building tools for precision gene therapy outcomes. Our team has been advancing the field of environmental influences on health, including the use of stem cell-derived mini-brains to understand how environmental chemicals modify brain development with seminal work in understanding RNA base editing signal transduction. We envision a new area of response genetics through iPSC and genetic integrations to pediatric vs adult disease onset from genetic contributions. In the area of critical care we use precision transcriptomics to explore how bacteria and viruses interact with a host immune system and contribute to unique patient immune responses and organ failure, including the identification of unique rare variants activated through nonsense-mediated decay suppression for viral-induced genetics. I have authored over 100 peer-reviewed papers, with 42 as the lead author.

Presentation(s):