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Concurrent

Late-Breaking Studies Affecting Patient Outcomes I

Sunday, March 22, 2026
3:15 PM - 4:15 PM Central Time
Location: Skyline Ballroom, W375D
CE: 1

    Late Breaker Moderator(s)

  • Ndidi Musa, MD, , FCCM

    Seattle Children's Hospital, Washington

    Disclosure information not submitted.

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Learning Objectives:

  • Evaluate evidence from a multinational phase II trial, which found that early endotracheal poractant alfa did not reduce duration of invasive mechanical ventilation or improve clinical outcomes in critically ill infants with bronchiolitis
  • Describe the key components of the OCEAN‑ICU tool
  • Examine the association between polyunsaturated fatty acid levels and organ injury in pediatric sepsis
  • Review current recommendations on procalcitonin use in the emergency department for suspected sepsis and describe the methods and primary findings of the UK PRONTO Trial
  • Analyze the relationship between age and life-sustaining therapy (LST) limitation by describing the Ethicus-2 age substudy and summarizing the adjusted odds of any LST limitation in patients aged 80 and older versus younger than 65

Presentations:

  • 3:20 PM - 3:30 PM Central Time
    Endotracheal Surfactant for Infants With Life-Threatening Bronchiolitis (BESS): A Randomised, Blinded, Sham-Controlled Phase II Trial

    Vithayathil JOHN Pappachan, MA, MBBChir, FRCA, FICM

  • 3:30 PM - 3:40 PM Central Time
    Development and Psychometric Testing of the OCEAN-ICU Instrument to Optimise Sedation Use in Intensive Care

    Ana Cristina Castro, PhD, MSc, BSc (she/her/hers) – University of York-Department of Health Sciences

  • 3:40 PM - 3:50 PM Central Time
    Plasma Linoleic Acid Is Associated With Pediatric Sepsis Phenotype and Acute Kidney Injury

    Ivan E. Saraiva, MD, MS – UPMC Presbyterian

  • 3:50 PM - 4:00 PM Central Time
    Procalcitonin and NEWS2 Evaluation for Timely Identification of Sepsis and Optimal Use of Antibiotics in the Emergency Department (PRONTO): A Multicentre, Randomised, Controlled, Open-Label, Phase 3 Trial

    Stacy Todd, PhD, FRCP (she/her/hers) – Tropical and Infectious Disease Unit, Royal Liverpool Hospital

  • 4:00 PM - 4:10 PM Central Time
    Influence of Age in End-of-Life Practices in Worldwide Intensive Care Units (Ethicus-2): A Prospective Observational Study

    Avneep Aggarwal, MD, FASA – Cleveland Clinic